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New research · Ophthalmology
Indian journal of ophthalmology · 4d
Cohort studyIndian journal of ophthalmology · 2026

Clinical profile and management outcomes of endophthalmitis cases in a tertiary retina unit: A five-year retrospective study.

Vijaya Sahu, Shivani Shrivastava, Aseem Kumar … Kirandeep Kaur
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OphthalmologyCohort study

Post-traumatic endophthalmitis was the leading cause of endophthalmitis in this cohort.

Clinical profile and management outcomes of endophthalmitis cases in a tertiary retina unit: A five-year retrospective study.

Vijaya Sahu … Kirandeep Kaur
Indian journal of ophthalmology · 2026
Purpose

To evaluate the clinical spectrum, microbiological profile, and visual outcomes of endophthalmitis cases managed at a tertiary retina unit in central India over a five-year period.

Methods

This retrospective study included 87 eyes of 87 patients diagnosed with endophthalmitis between January 2020 and December 2024.

n = 87 eyes
Results

traumatic eye injury caused most infections inside the eye, far more than other causes

63.2%
Post-traumatic
17.2%
Endogenous
11.5%
Post-operative
8%
Corneal ulcer-related
More results

The mean age at presentation was 35.2 ± 22 years, with males comprising 68.2%.

Visual acuity improved significantly post-intervention ( P = 0.008).

Patients presenting within 48 hours had better outcomes compared to delayed presentations ( P = 0.023).

More results

Those who received intravitreal antibiotics prior to pars plana vitrectomy showed significantly better visual outcomes ( P < 0.001).

“
Conclusion · 1 of 2

Post-traumatic endophthalmitis remains the leading cause in central India. Early presentation and timely intravitreal antibiotic administration significantly improve visual prognosis.

Conclusion · 2 of 2

These findings underscore the importance of prompt referral and intervention, especially in trauma-related cases, in optimizing outcomes and preserving vision.

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