Over 2,300 unique publications exist on high-flow nasal oxygen research.
High-flow nasal oxygen in perioperative and critical care: a bibliometric analysis.
Biao Xi … Di Zhang
Frontiers in medicine · 2026
Background
High-flow nasal oxygen (high-flow nasal oxygen), also known as high-flow nasal cannula, is an important noninvasive respiratory support strategy in perioperative and critical care practice.
Methods
We conducted a bibliometric and visual analysis of high-flow nasal oxygen research using English-language articles and reviews retrieved from the Web of Science Core Collection, Scopus, and PubMed for the period 2000-2025.
n = 2,314 unique publications
Results
2,314
the total distinct research articles about high-flow nasal oxygen
n = 2,314 unique publications
More results
High-flow nasal oxygen research showed sustained exponential growth, with marked acceleration after 2018 and especially after 2020.
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Conclusion · 1 of 3
High-flow nasal oxygen research has evolved from a focused literature on oxygenation support into a broader and more clinically differentiated field spanning perioperative and critical care practice.
Conclusion · 2 of 3
Current hotspots are increasingly centered on context-specific use, monitoring, failure prediction, and escalation decisions.
Conclusion · 3 of 3
Future research should prioritize clinically actionable patient stratification, standardized outcome definitions, and protocol-based integration of high-flow nasal oxygen across different care pathways.