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New research · Infectious Disease
RSC advances · 4d
StudyRSC advances · 2026

From cyclohexyl isocyanide and diaminomaleonitrile to functional 5-(alkylamino)-6-substituted pyrazine-2,3-dicarbonitriles: synthesis, X-ray structural elucidation, antimicrobial testing and OLED analysis.

Elizabeth John, Sushanta Lenka, Anil Kumar … Amal Al-Azmi
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Infectious DiseaseStudy

An OLED with 15 wt% of a new derivative showed superior performance.

From cyclohexyl isocyanide and diaminomaleonitrile to functional 5-(alkylamino)-6-substituted pyrazine-2,3-dicarbonitriles: synthesis, X-ray structural elucidation, antimicrobial testing and OLED analysis.

Elizabeth John … Amal Al-Azmi
RSC advances · 2026
15
Results
15
wt%
concentration of the derivative that led to better OLED performance
More results

New derivatives of 5-(alkylamino)-6-aryl/alkylpyrazine-2,3-dicarbonitriles were successfully synthesized with good to moderate yields through the reaction of alkyl isocyanides with aryl/alkyl carbonyl chlorides, followed by the incorporation of diaminomaleonitrile.

More results

The compounds were dispersed in a commercial 4,4'-bis( N -carbazolyl)-1,10-biphenyl host material and used for the formation of the emissive layer of OLEDs in concentration-dependent experiments.

“
Conclusion

The antibacterial and antifungal properties of the newly synthesized pyrazine-2,3-dicarbonitriles were evaluated.

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