Factors Associated with Favorable One-Year Outcomes After PreserFlo MicroShunt Implantation: Insights from…

Cohort studyAdvances in therapy· Jul 2026

Factors Associated with Favorable One-Year Outcomes After PreserFlo MicroShunt Implantation: Insights from Anterior Segment Optical Coherence Tomography.

Takahiro Minami, Daisuke Takemoto, Taro Muroya … Tomomi Higashide

GlaucomaCohort studyPrognosisQ1IF 4.5

Filtration toward the corneal limbus linked to lower risk of glaucoma surgery failure

Factors Associated with Favorable One-Year Outcomes After PreserFlo MicroShunt Implantation: Insights from Anterior Segment Optical Coherence Tomography.

Takahiro Minami … Tomomi Higashide

Advances in therapy · Jul 2026 · Q1 in General Medicine

Purpose

This study aimed to identify factors associated with favorable 1-year surgical outcomes after PreserFlo MicroShunt (PreserFlo MicroShunt) implantation, with a particular focus on baseline ocular anatomy and postoperative filtration patterns assessed by anterior segment optical coherence tomography (anterior segment optical coherence tomography).

Methods

This cohort study included individuals with primary open-angle or exfoliation glaucoma who underwent PreserFlo MicroShunt implantation.

HR, 0.28-0.57

Results

HR, 0.28-0.57

less limbus-directed drainage nearly doubled to triple the risk of surgery failing

More results

Median IOP decreased from 19 mmHg (interquartile range: 16-23.8) to 10 mmHg (8-13) at 12 months (p < 0.001).

Qualified success rates at 12 months were 56.8% for criterion A, 70.5% for criterion B, and 73.9% for criterion C.

Longer axial length was significant for criteria B and C (HR, 0.70 and 0.77; p = 0.002 and 0.008).

More results

Older age and exfoliation glaucoma were risk factors for hypotensive failure (HR, 1.05 and 3.75; p = 0.01 and 0.006).

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Conclusion · 1 of 2

Both baseline ocular anatomy, represented by axial length, and filtration toward the corneal limbus on anterior segment optical coherence tomography were independently associated with favorable 1-year outcomes following PreserFlo MicroShunt implantation.

Conclusion · 2 of 2

Integrating preoperative anatomical assessment with early postoperative imaging findings may help clinicians better understand individual surgical responses.

Factors Associated with Favorable One-Year Outcomes After PreserFlo MicroShunt Implantation: Insights from Anterior Segment Optical Coherence Tomography.

Factors Associated with Favorable One-Year Outcomes After PreserFlo MicroShunt Implantation: Insights from Anterior Segment Optical Coherence Tomography.

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