Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and…

StudyInvestigative ophthalmology & visual science· Apr 2025

Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.

Sophie Frank-Publig, Hrvoje Bogunovic, Klaudia Birner … Gregor S Reiter

RetinaStudyQ1IF 4.2

High-resolution optical coherence tomography measures thinner retinal pigment epithelium layers in geographic atrophy than standard optical coherence tomography.

Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.

Sophie Frank-Publig … Gregor S Reiter

Investigative ophthalmology & visual science · Apr 2025 · Q1 in Ophthalmology

Purpose

The purpose of this study was to investigate the benefits of a novel device with superior axial resolution.

Methods

Were recruited at the Department of Ophthalmology and Optometry at the Medical University of Vienna.

n = 40 eyes

Results

the light-sensing layer under the retina measured thinner with the new scanner

High-Res OCT (myoid zo

19.85µm

SPECTRALIS (myoid zone

21.37µm

More results

The study included 3920 B-scans of 40 eyes of 32 patients.

Smaller ellipsoid zone- and external limiting membrane loss areas (all P < 0.001) were found for the High-Res optical coherence tomography.

Higher subretinal drusenoid deposits volumes were found for the High-Res optical coherence tomography (P < 0.001).

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Conclusion · 1 of 2

Precise in vivo quantification of optical coherence tomography features is of great relevance for individualized patient management.

Conclusion · 2 of 2

The High-Res optical coherence tomography device allows for detailed topographical analysis of outer retinal changes in geographic atrophy, which could improve early detection, patient selection, and patient management in clinical practice.

Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.

Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.

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