Post

New research · Ophthalmology
Investigative ophthalmology & visual science · 5d
StudyInvestigative ophthalmology & visual science · 2025

Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.

Sophie Frank-Publig, Hrvoje Bogunovic, Klaudia Birner … Gregor S Reiter
Read paper
OphthalmologyStudy

High-resolution optical coherence tomography measures thinner retinal pigment epithelium layers in geographic atrophy than standard optical coherence tomography.

Quantifications of Outer Retinal Bands in Geographic Atrophy by Comparing Superior Axial Resolution and Conventional OCT.

Sophie Frank-Publig … Gregor S Reiter
Investigative ophthalmology & visual science · 2025
Purpose

The purpose of this study was to investigate the benefits of a novel device with superior axial resolution.

Methods

Were recruited at the Department of Ophthalmology and Optometry at the Medical University of Vienna.

n = 40 eyes
Results

the light-sensing layer under the retina measured thinner with the new scanner

High-Res OCT (myoid zo
19.85µm
SPECTRALIS (myoid zone
21.37µm
More results

The study included 3920 B-scans of 40 eyes of 32 patients.

Smaller ellipsoid zone- and external limiting membrane loss areas (all P < 0.001) were found for the High-Res optical coherence tomography.

Higher subretinal drusenoid deposits volumes were found for the High-Res optical coherence tomography (P < 0.001).

“
Conclusion · 1 of 2

Precise in vivo quantification of optical coherence tomography features is of great relevance for individualized patient management.

Conclusion · 2 of 2

The High-Res optical coherence tomography device allows for detailed topographical analysis of outer retinal changes in geographic atrophy, which could improve early detection, patient selection, and patient management in clinical practice.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cross-sectional
44.1%
had too much homocysteine in the blood, a far larger share than in dry AMD or healthy eyes
Cohort Study
92.3%
most laser-treated eyes had a favorable eye-structure outcome
Cohort Study
56%
lost three or more lines on the eye-chart vision test
Cohort Study
50%
older patients were more likely to lose three or more lines of vision
Study
81%
trials where mask air leaks were detected blowing toward the eyes
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Study
379 +/- 156 microm
lower thickness in the central retina, checked with an eye scan
Case Report
9 of 10 eyes
eyes had better measured vision after treatment