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Association Between Geriatric Assessment Scores and Corneal Biomechanical Parameters in Patients with Glaucoma.

New research · Ophthalmology

Biomedicines · 1mo

Cross-sectionalBiomedicines· Jul 2026

Association Between Geriatric Assessment Scores and Corneal Biomechanical Parameters in Patients with Glaucoma.

Yuto Yoshida, Yuri Fujino, Yuya Kato … Masaki Tanito

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GlaucomaCross-sectionalQ1IF 4.7

Lower frailty scores are associated with lower corneal resistance in glaucoma patients.

Association Between Geriatric Assessment Scores and Corneal Biomechanical Parameters in Patients with Glaucoma.

Yuto Yoshida … Masaki Tanito

Biomedicines · Jul 2026 · Q1 in General Medicine

Background

Multiple age-related systemic conditions, including frailty, cognitive impairment, and comorbid diseases, have been suggested to be associated with glaucoma.

Methods

This retrospective cross-sectional study included patients with glaucoma who attended the Department of Ophthalmology at Shimane University Hospital between May 2019 and August 2024.

n = 456 eyes

Results

Lower Geriatric 8 scores are associated with lower corneal resistance factor.

β 0.18 (95% CI 0.05 to 0.30)

null 0

0.05

0.30

CI excludes the null - significant

More results

The mean age was 70.2 ± 11.1 years, and 126 patients (45.0%) were women.

In contrast, no significant association was observed between G8 scores and corneal hysteresis (β = -0.02, 95% CI: -0.12 to 0.09).

Neither Mini-Cog nor Charlson Comorbidity Index was significantly associated with any ocular parameters.

“

Conclusion

In patients with glaucoma, frailty may be associated with corneal biomechanical properties, particularly corneal resistance factor and intraocular pressure-related parameters.

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