FULL-THICKNESS MACULAR HOLE IN AGE-RELATED MACULAR DEGENERATION PATIENTS WITH TWO DISTINCT ENTITIES: A Multicenter Study.
Degenerative full-thickness macular holes had more complete outer retinal atrophy than tractional holes.
FULL-THICKNESS MACULAR HOLE IN AGE-RELATED MACULAR DEGENERATION PATIENTS WITH TWO DISTINCT ENTITIES: A Multicenter Study.
To describe optical coherence tomography characteristics of full-thickness macular holes (full-thickness macular holes) in age-related macular degeneration patients.
A multicenter, retrospective, observational case series of patients diagnosed with age-related macular degeneration and full-thickness macular holes seen between January 1, 2009, and January 3, 2020.
A total of 86 eyes of 85 consecutive patients, with mean age of 80.31 ± 8.06 and mean best-corrected visual acuity of 1.17 ± 0.58 logarithm of the minimal angle of resolution.
Two different subtypes of full-thickness macular holes were identified: tractional and degenerative.
Fifty (58%) degenerative full-thickness macular holes characterized with inverted trapezoid appearance and 36 (42%) tractional full-thickness macular holes characterized with hourglass appearance.
Degenerative and tractional full-thickness macular holes may be two distinct clinical entities.
Discerning degenerative from tractional full-thickness macular holes is possible by using optical coherence tomography features including shape of the full-thickness macular holes, central macular thickness, internal-external ratio of full-thickness macular holes, and presence of complete retinal outer retinal atrophy, pigment epithelium detachment, and epiretinal membrane.