Rita EhrlichExperimental eye research10yFollowAnimal / preclinicalExperimental eye research · 2016Bevacizumab clearance through the iridocorneal angle following intravitreal injection in a rat model.Orly Gal-Or, Assaf Dotan, Mor Dachbash … Tami Livnat +4 moreRead paper Copy citationOphthalmologyAnimal / preclinicalLimited evidenceBevacizumab was no longer detected in eye drainage channels 48 h after injection.Bevacizumab clearance through the iridocorneal angle following intravitreal injection in a rat model.Orly Gal-Or … Tami LivnatExperimental eye research · 2016BackgroundAntivascular endothelial growth factor (antivascular endothelial growth factor) agents have been widely used for a variety of ocular disorders.48Results🎯 Predict48hno drug staining detected in the eye’s fluid-drainage channelsMore resultsThe etiology of sustained ocular hypertension following intravitreal administration of anti-VEGF agents is yet to be unraveled.Bevacizumab (25 mg/ml) was injected intravitreally after 3 days.Donkey anti-human IgG labeled with Alexa Fluor(®) 488 was used for bevacizumab immunoreactivity detection.More resultsAnti-CD31 antibody was used as a marker for Schlemm's canal endothelial cells.“ConclusionBevacizumab molecules passed through the aqueous outflow channels within 48 h after intravitreal bevacizumab injection.Read full abstractRead paper LikeCommentRepostSendPractice
