Post

Rita Ehrlich
The British journal of ophthalmology
21y
StudyThe British journal of ophthalmology · 2005

Augmented trabeculectomy in paediatric glaucoma.

R Ehrlich, M Snir, M Lusky … D D Gaton
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OphthalmologyStudy

After surgery, 75.8% of eyes had controlled eye pressure and stable or improved optic nerve cupping.

Augmented trabeculectomy in paediatric glaucoma.

R Ehrlich … D D Gaton
The British journal of ophthalmology · 2005
Purpose

To report the experience with trabeculectomy augmented with mitomycin C and 5-fluorouracil for the treatment of paediatric glaucoma.

Methods

Retrospective, interventional case series design was used.

n = 29 eyes
Results
75.8%
eyes with lower, controlled pressure and stable or improved optic nerve damage
n = 29 eyes
More results

Patient age at surgery ranged from 1 month to 8 years; most patients (n = 14, 82.3%) were aged less than 1 year (range 1 month-8 months, mean 3.95 (SD 2.56) months); three patients (17.7%) were aged 3, 5, and 8 years.

The duration of follow up was 3-120 months (mean 46 months).

More results

There was no significant change in cup/disc ratio: 0.1-0.8 (mean 0.42 (0.26)) before and 0.1-1.0 (mean 0.511 (0.27)) after (p = 0.45).

The life table success rate for intraocular pressure control remained stable at 86% at the 12, 24, and 36 months and after 48 months decreased to 53%.

“
Conclusion

Augmented trabeculectomy with mitomycin C and 5-fluorouracil may serve as the primary procedure in a selected group of paediatric patients with glaucoma.

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