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Cohort studyAmerican journal of ophthalmology · 2004

Photodynamic therapy of subfoveal choroidal neovascularization in high myopia in a clinical setting: visual outcome in relation to age at treatment.

Ruth Axer-Siegel, Rita Ehrlich, Dov Weinberger … Michal Kramer

OphthalmologyCohort study

Older patients had more severe vision loss after photodynamic therapy.

Photodynamic therapy of subfoveal choroidal neovascularization in high myopia in a clinical setting: visual outcome in relation to age at treatment.

Ruth Axer-Siegel … Michal Kramer

American journal of ophthalmology · 2004

Purpose

To evaluate the visual outcome of patients with myopic subfoveal choroidal neovascularization (choroidal neovascularization) given photodynamic therapy (photodynamic therapy) in a clinical setting, and to identify potential relation between the visual outcome and the age at treatment.

Methods

Twenty-nine consecutive patients (30 eyes) with subfoveal choroidal neovascularization caused by pathologic myopia who were treated with verteporfin photodynamic therapy from January 2000 to May 2003.

n = 30 eyes

Results

older patients were more likely to lose three or more lines of vision

50%

older age group

8%

younger age group

More results

The mean age was 63.1 years.

Patients received a mean of 3.48 treatments.

Mean visual acuity improved in the younger group from 0.63 to 0.39 logMAR (P = .02, paired t test) and deteriorated in the older group from 0.71 to 0.99 logMAR (P = .03, paired t test).

“

Conclusion

In our consecutive case series, visual prognosis of myopic choroidal neovascularization after photodynamic therapy was found to be influenced by age at treatment.

Post

Photodynamic therapy of subfoveal choroidal neovascularization in high myopia in a clinical setting: visual outcome in relation to age at treatment.

Older patients had more severe vision loss after photodynamic therapy.

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