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New research · Family Medicine
Nutrition reviews · 1d
Meta-analysisNutrition reviews · 2026

Health Economics of Primary Care Nutrition Interventions: a Systematic Review and Meta-Analysis.

Clara Wosser, Kyriaki Apergi, Sharleen O'Reilly
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Family MedicineMeta-analysis

Over half of primary care nutrition interventions were found to be cost-effective.

Health Economics of Primary Care Nutrition Interventions: a Systematic Review and Meta-Analysis.

Clara Wosser et al. · Nutrition reviews · 2026
Background

Non communicable diseases (NCDs) impose a major global health and economic burden, with poor diet recognized as a leading modifiable risk factor.

Purpose

We sought to systematically review and synthesize evidence on the cost-effectiveness of nutrition care interventions delivered by nutrition professionals in primary care, from both societal and health care system perspectives.

Methods

DATA EXTRACTION: Randomized controlled trials reporting economic evaluations of primary care nutrition interventions were eligible.

n = 25 included studies
56%
Results
56% of the reviewed nutrition interventions in primary care were deemed cost-effective.
n = 25 included studies
More results

The protocol was registered in PROSPERO under the number: CRD420251029435.

The meta-analysis employed random-effects models stratified by perspective.

Sensitivity analyses excluded influential outliers.

SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration No. [CRD420251029435].

“
Conclusion · 1 of 3

Among 25 included studies, 56% were cost-effective and 20% were moderately cost-effective.

Conclusion · 2 of 3

Pooled INB favored cost-effectiveness from a societal perspective (€650.32), while the health care system perspective indicated initial investment requirements (-€402.65).

Conclusion · 3 of 3

Telehealth delivery and diabetes-focused interventions demonstrated the strongest economic outcomes. Despite high heterogeneity, sensitivity analyses improved pooled estimates, reinforcing the robustness of findings.

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