Sinonasal squamous cell carcinoma: REFCOR guidelines for diagnosis, treatment and follow-up.

GuidelineEuropean annals of otorhinolaryngology, head and neck diseases· Jun 2026

Sinonasal squamous cell carcinoma: REFCOR guidelines for diagnosis, treatment and follow-up.

B Vérillaud, F Chatelet, A-C Baglin … P Herman

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SurgeryGuidelineClinical practiceQ2IF 1.1

Patients with sinonasal squamous cell carcinoma should be monitored for at least 5 years.

Sinonasal squamous cell carcinoma: REFCOR guidelines for diagnosis, treatment and follow-up.

B Vérillaud … P Herman

European annals of otorhinolaryngology, head and neck diseases · Jun 2026 · Q2 in Surgery

Purpose

The authors present the guidelines of the REFCOR French expert network for rare head-and-neck cancers for the management of sinonasal squamous cell carcinoma (sinonasal squamous cell carcinoma).

Methods

A multidisciplinary working group conducted a literature review on the topic.

Results

patients with this cancer should be checked for a minimum recommended time

First 2 years

4times

3rd year

3times

Until 5th year

2times

More results

Strong agreement: due to the risk of malignant transformation, resection is recommended for sinonasal inverted papilloma; facial CT and MRI are recommended for local extension assessment.

“

Conclusion

Disagreement: systematic induction chemotherapy before surgery is not recommended; in case of orbital extension, induction chemotherapy followed by concomitant chemoradiotherapy should be discussed.

Sinonasal squamous cell carcinoma: REFCOR guidelines for diagnosis, treatment and follow-up.

Sinonasal squamous cell carcinoma: REFCOR guidelines for diagnosis, treatment and follow-up.

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