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New research · Anesthesiology
A&A practice · 1d
Cohort studyA&A practice · 2026

Association Between Continuously Recorded ST Changes and Perioperative Myocardial Injury: An Explorative Prospective Cohort Study.

Arman Valadkhani, Samuel Bruchfeld, Anil Gupta … Max Bell
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AnesthesiologyCohort study

ST-depression is associated with a higher rate of perioperative myocardial injury.

Association Between Continuously Recorded ST Changes and Perioperative Myocardial Injury: An Explorative Prospective Cohort Study.

Arman Valadkhani et al. · A&A practice · 2026
Background

Perioperative myocardial injury (PMI) is associated with a higher mortality after noncardiac surgery.

Purpose

This study explored the association between continuous perioperative ST-segment monitoring and PMI in patients undergoing intermediate- to high-risk vascular surgery.

Methods

This was a prospective, single-center cohort study.

n = 498 patients
Results

ST-depression, a specific heart signal, means a much higher risk of heart injury around surgery

RR 3.85 (95% CI 1.86 to 7.94)
null = 11.867.94
CI excludes the null - significant
More results

Absolute ST-segment deviation >1 mm from individualized lead baseline was also associated with PMI (RR, 2.03; 95% CI, 1.01-4.06; P = .046).

More results

When ST-depression was added to the baseline model, including age and the American Society of Anesthesiologists (ASA) physical status classification system, overall net risk classification improved (NRI, 0.50; 95% CI, 0.16-0.86).

“
Conclusion

ST-depression meeting universal myocardial infarction criteria and ST deviations >1 mm from individualized baseline were associated with PMI. Intra- and postoperative ST-segment monitoring may facilitate detection of PMI.

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