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New research · Obstetrics & Gynecology
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 1d
Randomized trialSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026

Milk of magnesia in enhanced recovery after surgery for preventing postoperative ileus after hysterectomy: randomized controlled trial.

Wathirada Karnchanabanyong, Irene Ruengkhachorn, Nida Jareemit … Sompop Kuljarusnont
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Obstetrics & GynecologyRandomized trial

Milk of magnesia significantly reduced postoperative ileus after hysterectomy.

Milk of magnesia in enhanced recovery after surgery for preventing postoperative ileus after hysterectomy: randomized controlled trial.

Wathirada Karnchanabanyong et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
Purpose

To evaluate whether adding milk of magnesia (MOM) to an enhanced recovery after surgery (ERAS) pathway prevents postoperative ileus (POI) and improves postoperative bowel function.

Methods

Were randomly assigned to ERAS alone (n = 80) or ERAS plus MOM (n = 80).

3.8%
Results
vs 27.5%
fewer patients experienced delayed bowel function after surgery with milk of magnesia
More results

Among 160 patients, 60 (37.5%) had gynecologic malignancies: endometrial cancer (n = 34), ovarian cancer (n = 16), cervical cancer (n = 8), and leiomyosarcoma (n = 2).

Time to well-tolerated solid diet was significantly shorter in the MOM group compared with the control group (20.6 ± 10.9 vs 28.8 ± 16.3 h; P < 0.001).

More results

Patient-reported outcomes favored the MOM group, with higher eating and daily activity satisfaction scores.

No severe adverse events occurred in the MOM group.

“
Conclusion

Adding MOM to ERAS was associated with reduced POI incidence and faster recovery of bowel function in patients undergoing abdominal hysterectomy for benign or malignant conditions.

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