Benchmarking outcomes of endoscopic retrograde cholangio-pancreatography for malignant biliary obstructions…

Cohort studyDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver· Jul 2026

Benchmarking outcomes of endoscopic retrograde cholangio-pancreatography for malignant biliary obstructions: A multicenter real-world study.

Binda Cecilia, Cucchetti Alessandro, Anderloni Andrea … i-EUS Group

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GastroenterologyCohort studyClinical practiceQ1IF 3.2

ERCP for malignant biliary obstruction achieved high technical success.

Benchmarking outcomes of endoscopic retrograde cholangio-pancreatography for malignant biliary obstructions: A multicenter real-world study.

Binda Cecilia … i-EUS Group

Digestive and liver disease · Jul 2026

Background

Endoscopic retrograde cholangiopancreatography (endoscopic retrograde cholangiopancreatography) quality measures are critical to define standards of care and guide improvement strategies.

Purpose

This study aimed to determine risk-adjusted outcomes following endoscopic retrograde cholangiopancreatography for malignant biliary obstruction(malignant biliary obstruction).

Methods

Using an intention-to-treat approach, we analyzed data from a multicenter database including 23 Italian hospitals (2017-2022).

n = 3148

91.3%

Results

91.3%

the ERCP procedure successfully cleared blocked bile ducts caused by cancer

n = 3148

More results

Clinical and procedural characteristics showed considerable heterogeneity across centers (I²>75%).

Post-ERCP pancreatitis occurred in 5.4% (intraclass correlation coefficient 12.9%), additional ERCPs were required in 23.7% (intraclass correlation coefficient 4.1%), and 30-day mortality was 4.2%.

More results

Treatment in high-volume hospitals (>350ERCPs/year) was associated with lower mortality(p = 0.001).

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Conclusion · 1 of 3

Most variability in endoscopic retrograde cholangiopancreatography outcomes across hospitals reflects differences in patient selection and technical strategies.

Conclusion · 2 of 3

After risk adjustment, outcomes were similar across centers, supporting consistent quality of care.

Conclusion · 3 of 3

This study provides exploratory, risk-adjusted benchmarks derived from real-world practice for endoscopic retrograde cholangiopancreatography in malignant biliary obstruction and supports their use for quality monitoring and referral planning.

Benchmarking outcomes of endoscopic retrograde cholangio-pancreatography for malignant biliary obstructions: A multicenter real-world study.

Benchmarking outcomes of endoscopic retrograde cholangio-pancreatography for malignant biliary obstructions: A multicenter real-world study.

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