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New research · Allergy & Immunology
Anaesthesia, critical care & pain medicine · 2d
GuidelineAnaesthesia, critical care & pain medicine · 2026

Guidelines: Diagnosis and management of perioperative immediate hypersensitivity reactions 2025.

Mertes Paul Michel, Chiriac Anca, Tacquard Charles … Demoly Pascal
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Allergy & ImmunologyGuideline

Experts developed 70 recommendations for perioperative hypersensitivity reactions.

Guidelines: Diagnosis and management of perioperative immediate hypersensitivity reactions 2025.

Mertes Paul Michel et al. · Anaesthesia, critical care & pain medicine · 2026
Purpose

The French Society of Anaesthesia and Intensive Care (SFAR) and the French Society of Allergology (SFA) have collaborated to propose guidelines for the diagnosis and management of perioperative immediate hypersensitivity reactions (IHR).

Methods

A group of 23 French experts from the SFAR and the SFA was assembled.

n = 23 French experts
Results

experts agreed on guidelines for allergic reactions during or after surgery

high level of evidence
6
low level of evidence
16
expert opinions
48
More results

Of these recommendations, 6 have a high level of evidence (6 GRADE 1), 16 have a low level of evidence (16 GRADE 2) and 48 are expert opinions.

Finally, for 1 question, no recommendation could be made.

“
Conclusion

There was strong agreement among the experts to formulate recommendations aimed at providing a benchmark for the diagnosis and management of perioperative IHR.

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