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Cohort studyCVIR endovascular · 2026

Percutaneous intrabiliary injection of gelatin sponge slurry for the management of acute hemobilia during biliary interventions: an alternative salvage technique.

Trieu Hai Pham, Nhat Minh Nguyen, Linh Chi Ho … Quyet Ta Nguyen

Infectious DiseaseCohort study

Intrabiliary Gelfoam slurry was associated with immediate bleeding control in all hemobilia cases.

Percutaneous intrabiliary injection of gelatin sponge slurry for the management of acute hemobilia during biliary interventions: an alternative salvage technique.

Trieu Hai Pham et al. · CVIR endovascular · 2026

Purpose

To evaluate percutaneous intrabiliary injection of gelatin sponge (Gelfoam) slurry as a preliminary salvage technique for acute hemobilia during biliary interventions when angiographic embolization is unavailable.

Methods

We retrospectively reviewed eight patients with significant hemobilia during percutaneous biliary procedures between September 2024 and December 2025.

Results

immediate bleeding control was achieved in all patients

More results

One instance of recurrent bleeding at 10 days was successfully managed with a repeat injection.

Post-procedural infectious episodes (fever, leukocytosis) were observed in two patients (25%), requiring an upgrade in targeted antibiotic therapy.

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Conclusion · 1 of 2

Preliminary experience suggests that intrabiliary Gelfoam slurry may represent a potential bridging or salvage maneuver for acute hemobilia in resource-constrained scenarios.

Conclusion · 2 of 2

However, because it relies on internal compression rather than definitive vascular repair, and carries potential risks of infectious exacerbation, it should be applied cautiously with strict follow-up and does not replace definitive transcatheter arterial embolization.

Percutaneous intrabiliary injection of gelatin sponge slurry for the management of acute hemobilia during biliary interventions: an alternative salvage technique.

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