Low-dose intrathecal morphine versus intrathecal fentanyl for post-caesarean analgesia in a resource-constrained setting: a pragmatic randomised trial.

In this single-centre pragmatic trial conducted in a South African public-sector hospital, low-dose intrathecal morphine at both 50 µg and 100 µg reduced 24-hour postoperative opioid requirements after caesarean delivery compared with intrathecal fentanyl 25 µg.

These findings additionally support 50 µg intrathecal morphine as an effective and implementable option for post-caesarean analgesia in resource-constrained obstetric settings.