Significance of Phrenic Nerve Conduction Study in the Electrodiagnosis of Guillain Barré Syndrome.

Cohort studyJournal of the peripheral nervous system : JPNS· Jun 2026

Significance of Phrenic Nerve Conduction Study in the Electrodiagnosis of Guillain Barré Syndrome.

Volkan Tasdemir, Nermin Gorkem Sirin, Sezin Alpaydın Baslo … Elif Kocasoy Orhan

Read paper

NeuromuscularCohort studyDiagnosisQ2IF 2.8

Phrenic nerve conduction study distinguishes demyelinating Guillain-Barré subtype with high accuracy.

Significance of Phrenic Nerve Conduction Study in the Electrodiagnosis of Guillain Barré Syndrome.

Volkan Tasdemir … Elif Kocasoy Orhan

Journal of the peripheral nervous system · Jun 2026 · Q2 in Neurology

Background

To determine the role of phrenic nerve conduction studies (nerve conduction studies) in identifying subtypes of Guillain-Barré syndrome (GBS) and to investigate the correlations between phrenic nerve conduction studies and clinical and respiratory scores.

Methods

A clinical evaluation was conducted on 23 patients diagnosed with GBS, encompassing the Medical Research Council (Medical Research Council) sum scores, GBS disability scores, and Erasmus GBS Respiratory Insufficiency Scores (Erasmus GBS Respiratory Insufficiency Scores).

n = 23 patients

87.0%

Results

87.0%

sensitivity

correctly flags most demyelinating cases, fewer are missed

n = 23 patients

More results

Most of the phrenic compound muscle action potential parameters revealed moderate correlations with clinical scores and with the results of median and ulnar EDX studies.

“

Conclusion

Besides its importance for having correlations with clinical and respiratory features, phrenic nerve conduction studies may improve the diagnostic sensitivity in differentiating GBS subtypes.

Significance of Phrenic Nerve Conduction Study in the Electrodiagnosis of Guillain Barré Syndrome.

Significance of Phrenic Nerve Conduction Study in the Electrodiagnosis of Guillain Barré Syndrome.

Related papers