Henoch-Schoenlein purpura-like lesions in IL12RB1 and IL12B defects-a multi-centric experience from India.

Rarely, patients with IL12RB1/IL12B defects can exhibit cutaneous manifestations such as Henoch-Schonlein purpura (Henoch-Schonlein purpura).

In our cohort, eight patients had IL12RB1 defect, and one had IL12B defect.

Concurrent infections due to Salmonella sp. and Pandorea apista were documented in 44.4% (n = 4) and 22.2% (n = 2), respectively.

The Henoch-Schonlein purpura-like vasculitic rash usually occurred in setting of underlying bacterial infections in patients with particularly IL12RB1/IL12B defects.