Unilateral Biportal Endoscopic Discectomy vs Percutaneous Interlaminar Endoscopic Discectomy for L5 to S1…

StudyInternational journal of spine surgery· Jul 2026

Unilateral Biportal Endoscopic Discectomy vs Percutaneous Interlaminar Endoscopic Discectomy for L5 to S1 Disc Herniation: A Prospective Comparative Study With Quasirandom Allocation.

Guanyi Liu, Zihui Yang, Qing Li … Miao Zhu

SpineStudyTreatmentQ1IF 1.9

Percutaneous interlaminar endoscopic discectomy had shorter operative time than unilateral biportal endoscopic discectomy for L5-S1 disc herniation

Unilateral Biportal Endoscopic Discectomy vs Percutaneous Interlaminar Endoscopic Discectomy for L5 to S1 Disc Herniation: A Prospective Comparative Study With Quasirandom Allocation.

Guanyi Liu … Miao Zhu

International journal of spine surgery · Jul 2026 · Q1 in Surgery

Purpose

To compare the clinical efficacy and perioperative outcomes of percutaneous interlaminar endoscopic discectomy (percutaneous interlaminar endoscopic discectomy) and unilateral biportal endoscopic discectomy (unilateral biportal endoscopic discectomy) in treating L5 to S1 lumbar disc herniation.

Methods

This prospective comparative study with quasirandom allocation included 59 patients with diagnosed isolated L5 to S1 disc herniation who underwent either percutaneous interlaminar endoscopic discectomy ( n = 30) or unilateral biportal endoscopic discectomy ( n = 29) between January 2023 and June 2024.

n = 59 patients

Results

Percutaneous interlaminar endoscopic discectomy cut operative time roughly in half versus unilateral biportal endoscopic discectomy

58.2minute

PIED

109.6minute

UBED

More results

Both percutaneous interlaminar endoscopic discectomy and unilateral biportal endoscopic discectomy groups demonstrated significant postoperative improvements in lumbar and leg pain visual analog scale scores and Oswestry Disability Index scores ( P < 0.001).

More results

Additionally, the percutaneous interlaminar endoscopic discectomy group had lower lumbar pain visual analog scale scores at final follow-up (0.6 ± 0.6 vs 1.2 ± 0.9, P < 0.05).

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Conclusion · 1 of 3

Both unilateral biportal endoscopic discectomy and percutaneous interlaminar endoscopic discectomy are safe and effective techniques for treating L5 to S1 disc herniation.

Conclusion · 2 of 3

However, percutaneous interlaminar endoscopic discectomy is associated with shorter operative time, faster postoperative recovery, and less early postoperative lumbar pain.

Conclusion · 3 of 3

These findings support the preferential use of percutaneous interlaminar endoscopic discectomy in selected patients with isolated L5 to S1 disc herniation.

Unilateral Biportal Endoscopic Discectomy vs Percutaneous Interlaminar Endoscopic Discectomy for L5 to S1 Disc Herniation: A Prospective Comparative Study With Quasirandom Allocation.

Unilateral Biportal Endoscopic Discectomy vs Percutaneous Interlaminar Endoscopic Discectomy for L5 to S1 Disc Herniation: A Prospective Comparative Study With Quasirandom Allocation.

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