Efficacy and safety profile of volume-staged stereotactic radiosurgery for ruptured, large pediatric arteriovenous malformations: a multicenter cohort analysis.

The cumulative obliteration rate was 37% at 5 years and 56% at 10 years.

Patients with a nidus volume of ≤ 10 cm3 had significantly higher cumulative obliteration rates than those with a nidus volume > 10 cm3 (log-rank test, p = 0.021).

Similarly, patients treated with a prescription dose > 17 Gy showed significantly higher cumulative obliteration rates compared to those treated with a dose ≤ 17 Gy (log-rank test, p = 0.012).