AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection…

AI / informaticsThe American journal of gastroenterology· Aug 2026

AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection rate: a multicenter randomized controlled trial.

Yusuke Nishikawa, Ai Fujimoto, Yorihito Hayashi … Takahisa Matsuda

Medical Imaging AIAI / informaticsDiagnosis

Artificial intelligence-assisted second forward-view examination significantly improved right colon adenoma detection rate.

AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection rate: a multicenter randomized controlled trial.

Yusuke Nishikawa … Takahisa Matsuda

The American journal of gastroenterology · Aug 2026

Background

Adenomas in the right colon are likely to be missed during colonoscopy because of anatomical complexity and lesion characteristics.

Purpose

This multicenter randomized controlled trial aimed to compare standard colonoscopy with an artificial intelligence-assisted second forward-view examination of the right colon to determine whether this strategy improves the adenoma detection rate (adenoma detection rate).

Methods

Undergoing colonoscopy were randomly assigned in a 1:1 ratio to either the artificial intelligence-assisted colonoscopy group (artificial intelligence group) or the standard colonoscopy group (non-artificial intelligence group).

n = 606 patients

8.5%

Results

8.5%

absolute increase in right colon adenoma detection rate with artificial intelligence assistance

n = 606 patients

More results

The improvement was driven by increased detection of small, flat lesions and those in anatomically challenging regions, such as the ascending colon.

Subgroup analyses showed consistent improvement in the right colon adenoma detection rate with artificial intelligence assistance regardless of endoscopist experience.

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Conclusion · 1 of 2

The artificial intelligence-assisted second forward-view examination significantly improved the right colon adenoma detection rate.

Conclusion · 2 of 2

This combined strategy may improve adenoma detection in the right colon regardless of endoscopist experience. However, the independent contribution of artificial intelligence assistance warrants further investigation.

AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection rate: a multicenter randomized controlled trial.

AI-assisted second forward-view examination of the right colon significantly improves the adenoma detection rate: a multicenter randomized controlled trial.

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