Respiratory support in paediatric patients with bronchiolitis: a systematic review and meta-analysis.

High-flow nasal cannula did not reduce the need for mechanical ventilation compared to low-flow nasal cannula (risk ratio 0.69, 95% CI 0.33-1.44; p=0.32) or continuous positive airway pressure (risk ratio 0.90, 95% CI 0.65-1.24; p=0.52).

High-flow nasal cannula was associated with significant reduction in length of paediatric intensive care unit (paediatric intensive care unit) stay compared to low-flow nasal cannula (mean difference (MD) -0.40 95% CI -0.78- -0.02; p=0.04), but not compared to continuous positive airway pressure (MD -0.24, 95% CI -0.91-0.43; p=0.47).