Rhinovirus Species in Acute Respiratory Tract Infections and the Risk of Asthma in Children. | ScholarDeck

Paper

Rhinovirus Species in Acute Respiratory Tract Infections and the Risk of Asthma in Children.

New research · Pediatrics

Pediatric pulmonology · 2mo

Case-controlPediatric pulmonology· Aug 2026

Rhinovirus Species in Acute Respiratory Tract Infections and the Risk of Asthma in Children.

Ville Forsström, Matti Waris, Ville Peltola, Laura Toivonen

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Pediatric RespiratoryCase-controlQ1IF 2.1

Early RV-A or RV-C wheezing illnesses linked to higher childhood asthma risk

Rhinovirus Species in Acute Respiratory Tract Infections and the Risk of Asthma in Children.

Ville Forsström … Laura Toivonen

Pediatric pulmonology · Aug 2026 · Q1 in Pediatrics

Background

Rhinoviruses (rhinoviruses) are the most common pathogens causing respiratory tract infections, and early childhood rhinoviruses wheezing illnesses are a known risk factor for childhood asthma.

Methods

We conducted a nested case-control study in a birth cohort of 923 children followed prospectively from birth to age 7 years.

n = 923 children

Results

early RV-C wheezing illness raised later asthma risk

OR 1.66 (95% CI 1.11 to 2.49)

null 1

1.11

2.49

CI excludes the null - significant

More results

We identified 56 cases and 168 matched controls.

In total, 807 rhinoviruses-positive samples were successfully classified.

RV-A, RV-B, or RV-C positive URTIs were not associated with asthma risk.

“

Conclusion

Both RV-A and RV-C -induced early wheezing illnesses were associated with an increased risk of childhood asthma. Acute URTIs caused by RV-A, RV-B, or RV-C were not associated with asthma risk.

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