Comparative study of Adjunct Imaging Modalities in Dense breast (AdMoB-D study).
Contrast-enhanced mammography detected all cancers in diagnostic dense-breast cohort
Comparative study of Adjunct Imaging Modalities in Dense breast (AdMoB-D study).
To compare the diagnostic accuracy of contrast-enhanced mammography (contrast-enhanced mammography) with digital mammography (digital mammography), digital breast tomosynthesis (digital breast tomosynthesis) and ultrasonography (ultrasonography) for breast cancer detection in dense breasts.
This prospective study was conducted between January 2023 and 2025 including digital mammography with ACR- C or D category parenchymal density.
It also demonstrated higher specificity (94.3%) and strongest association with malignancy in surveillance group.
Agreement with histopathology was highest for contrast-enhanced mammography (κ 0.80).
Contrast-enhanced mammography demonstrates superior diagnostic accuracy than conventional mammographic techniques in dense breasts, with excellent sensitivity, negative predictive value and agreement with histopathology.
ADVANCES IN KNOWLEDGE: contrast-enhanced mammography improves cancer detection and disease extent assessment in dense breasts, enabling confident exclusion of malignancy and more accurate staging.
Its high diagnostic performance supports use as practical adjunct, particularly in resource-limited settings.