Dietary supplements were associated with fewer anti-VEGF injections in wet age-related macular degeneration.
AREDS2 Supplementation in Patients with Wet Age-Related Macular Degeneration.
Nidal Siag … Idit Maharshak
The Israel Medical Association journal · Oct 2023
Background
In recent years, major progress has been made in treating the wet form of age-related macular degeneration (AMD) with anti-vascular endothelial growth factors, which reportedly stabilize and improve vision.
Purpose
To examine the effect of dietary supplementation, as recommended by the Age-Related Eye Disease Study 2 (AREDS2), on the number of anti-vascular endothelial growth factor injections administered to patients with wet AMD.
Methods
A retrospective study was conducted with 57 participants (27 participants in the study group and 30 in the control group) receiving injections of anti-vascular endothelial growth factors.
n = 57 participants
Results
Patients with supplements averaged 21.89 injections over 3 years, vs. 26.00 without.
21.89inject
study group
26inject
control group
More results
Final visual acuities were 0.45 ± 0.45 and 0.8 ± 0.73 (P = 0.09), and final central macular thicknesses were 288.26 ± 55.38 and 313.12 ± 107.36 (P = 0.38) in the study and control groups, respectively.
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Conclusion · 1 of 2
The average number of injections after 3 years was lower in the study group, but this difference did not reach statistical significance.
Conclusion · 2 of 2
No statistically significant difference was found in final visual acuity or central macular thickness between the groups.
