Quality of Life and Functional Outcomes After Watch-and-Wait for Locally Advanced Rectal Cancer: A Meta-analysis.

Of 617 screened studies, 28 were reviewed in full and 9 met inclusion criteria (total 923 patients).

Meta-analysis of five studies (n = 601) with no statistically significant difference in overall quality of life between groups (pooled mean difference = 0.10, 95% confidence interval: -0.19 to 0.39, P = 0.49).

Qualitative synthesis of low anterior resections syndrome scores outcomes favored W&W.