Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of…

Systematic reviewFrontiers in medicine· 2026

Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of Science, Scopus, and PubMed (1973-2025).

Shiyang Yu, Wen Yang, Rui Luo … Min Liu

GeriatricsSystematic reviewQ1IF 3.4

The United States produced 21.9% of all hypertension-and-frailty publications, more than any country.

Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of Science, Scopus, and PubMed (1973-2025).

Shiyang Yu … Min Liu

Frontiers in medicine · 2026 · Q1 in General Medicine

Background

Hypertension and frailty frequently coexist in older adults and jointly increase the risks of falls, hospitalization, disability, and mortality.

Purpose

This study aimed to characterize the intellectual landscape of hypertension and frailty research using a multi-database bibliometric approach.

Methods

English-language publications were retrieved from the Web of Science Core Collection (Web of Science Core Collection), Scopus, and PubMed.

n = 1,853 records

Results

Nearly one in four papers on this topic came from US-based researchers.

United States

21.9%

China

10.9%

Italy

7.7%

More results

Publications were sparse from 1973 to 2000, increased after 2000, accelerated after 2010, and rose sharply after 2015, approaching 1,000 in 2023.

CiteSpace identified recent citation bursts for "frailty index" and "hypertension management." The PURE study ranked first in global citations, while the SPRINT trial in adults aged ≥75 years ranked first in local citations.

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Conclusion · 1 of 2

Research on hypertension and frailty has grown rapidly, especially after 2015, forming a knowledge structure focused on hypertension management, frailty assessment, and functional outcomes.

Conclusion · 2 of 2

Future studies should address multimorbid populations, prioritize functional endpoints, and validate combined blood pressure control and function-oriented interventions in real-world settings.

Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of Science, Scopus, and PubMed (1973-2025).

Hypertension and frailty in older adults: a bibliometric analysis and knowledge mapping based on Web of Science, Scopus, and PubMed (1973-2025).

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