Intra-Individual Variability of Myocardial Blood Flow and Flow Reserve Assessed by [ 15 O]H 2 O-PET in Patients with Angina and No Obstructive Coronary Disease.

Twenty-one patients (mean age 70 ± 8.2 years; 48% female) underwent repeated scans with a median interval of 21 days.

0.92 ± 0.22 mL/min/g (r = 0.87; repeatability coefficient 0.23 mL/min/g; coefficient of variation 9%; intraclass correlation coefficient 0.87).

2.97 ± 0.78 mL/min/g (r = 0.83; repeatability coefficient 0.98 mL/min/g; coefficient of variation 11.6%; intraclass correlation coefficient 0.81).

Neither expert re-evaluation nor rate-pressure product correction of the resting myocardial blood flow improved the reproducibility.