From Dynamics to Diagnosis and Therapy: A Multiscale Computational Framework for MALT1-Targeted Cancer Theranostics.

In the role of cancer-related targets, MALT1 shows great potential as a cancer biomarker, being related to the nuclear factor-κB (NF-κB) signaling activation, an important biochemical process that regulates immune responses and inflammatory events in the human body, and its malfunction is related to the development and survival of several types of cancer.

Despite MALT1's importance as a cancer target, to the best of our knowledge, there is a lack of literature proposing chemical agents capable of treating and diagnosing cancer through this biomarker.