Systemic Inflammatory Burden Is Independently Associated with Anemia After Transcatheter Aortic Valve…

Cohort studyBiomedicines· Jul 2026

Systemic Inflammatory Burden Is Independently Associated with Anemia After Transcatheter Aortic Valve Implantation in Patients Referred to Cardiac Rehabilitation.

Theodor Constantin Stamate, Radu Sebastian Gavril, Mihai Roca … Florin Mitu

Cardiopulmonary RehabilitationCohort studyQ1IF 4.7

Higher systemic immune-inflammation index independently linked to post-transcatheter aortic valve implantation anemia.

Systemic Inflammatory Burden Is Independently Associated with Anemia After Transcatheter Aortic Valve Implantation in Patients Referred to Cardiac Rehabilitation.

Theodor Constantin Stamate … Florin Mitu

Biomedicines · Jul 2026 · Q1 in General Medicine

Background

Anemia is frequently observed in patients undergoing transcatheter aortic valve implantation (transcatheter aortic valve implantation) and may reflect persistent biological vulnerability in the post-procedural period.

Methods

This retrospective observational study included 80 consecutive patients referred to cardiac rehabilitation after successful transcatheter aortic valve implantation.

Results

worse immune-inflammation balance nearly quintuples anemia odds

OR by subgroup · 95% CI

More results

Anemia was present in 67.5% of patients at cardiac rehabilitation entry.

Area under the ROC curve (AUC) was 0.70 for neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, 0.68 for SII, and 0.67 for c-reactive protein.

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Conclusion · 1 of 2

Systemic inflammatory burden is independently associated with anemia at the time of entry into cardiac rehabilitation facility after transcatheter aortic valve implantation.

Conclusion · 2 of 2

These findings support an integrated approach to patient evaluation and provide a basis for future mechanistic and interventional studies.

Systemic Inflammatory Burden Is Independently Associated with Anemia After Transcatheter Aortic Valve Implantation in Patients Referred to Cardiac Rehabilitation.

Systemic Inflammatory Burden Is Independently Associated with Anemia After Transcatheter Aortic Valve Implantation in Patients Referred to Cardiac Rehabilitation.

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