High-Sensitivity Troponin I and NT-proBNP as Early Indicators of Disease Severity and Prognostic Markers in Immune Checkpoint Inhibitor-Associated Fulminant Myocarditis.

Hs-cTnI and NT-proBNP levels at presentation are strong indicators of myocardial injury severity and ventricular dysfunction in immune checkpoint inhibitor-associated myocarditis.

Their measurement facilitates early risk stratification, identifying patients at highest risk for fulminant disease who may benefit from intensive monitoring and timely intervention.

Additionally, pre-existing cardiovascular comorbidities remain crucial for identifying vulnerable populations prior to immune checkpoint inhibitor initiation.