Association of high-sensitivity troponin with advanced fibrosis in metabolic dysfunction-associated steatotic liver disease and the potential mediating role of inflammation: A cross-sectional study of NHANES, 1999 to 2004.

Notably, cardiovascular disease (cardiovascular disease) represents the leading cause of mortality in this population.

Moreover, we conducted a mediation analysis to explore the role of inflammation, as represented by the monocyte-to-lymphocyte ratio, in the aforementioned association.

Among 4684 patients without cardiovascular disease, 169 had advanced liver fibrosis.

Additionally, receiver operating characteristic analysis indicated that at a cutoff of 7.28 ng/L, hs-troponin T predicted advanced liver fibrosis with an area under the curve of 0.85 (95% confidence interval: 0.82-0.88).