Preoperative High-Sensitivity Troponin and Risk of In-Hospital Mortality and Cardiac Events after Hip…

Cohort studyJournal of orthopaedic trauma· Jul 2026

Preoperative High-Sensitivity Troponin and Risk of In-Hospital Mortality and Cardiac Events after Hip Fracture Surgery.

Aly S Toure, Kenechukwu Okafor, Bryan Medilien … Mara Schenker

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Acute Chest Pain & TroponinCohort studyPrognosisQ1IF 2.0

Significantly elevated preoperative troponin linked to 16-fold higher odds of cardiac events, death

Preoperative High-Sensitivity Troponin and Risk of In-Hospital Mortality and Cardiac Events after Hip Fracture Surgery.

Aly S Toure … Mara Schenker

Journal of orthopaedic trauma · Jul 2026 · Q1 in General Medicine

Purpose

To evaluate whether preoperative hs-cTn elevation predicted in-hospital cardiac events and mortality following hip fracture surgery, and whether surgical delay modified this relationship.

Methods

Single Level 1 trauma center in the United States.

n = 510 patients

Results

significantly elevated troponin sharply raises risk of cardiac events or death

OR 16.10 (95% CI 3.60 to 72.40)

CI excludes the null - significant

More results

Mean age was 76.3 ± 14.1 years, and 291 patients (57.1%) were female.

Thirty-five patients (6.9%) experienced the composite outcome.

The composite outcome occurred in 19 of 424 patients (4.5%) with normal troponin, 6 of 58 patients (10.3%) with elevated troponin, and 10 of 28 patients (35.7%) with significantly elevated troponin (p < 0.001).

More results

Mortality occurred in 8 of 424 patients (1.9%), 2 of 58 patients (3.4%), and 3 of 28 patients (10.7%), respectively (p = 0.015).

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Conclusion · 1 of 2

Preoperative high-sensitivity cardiac troponin elevation was independently associated with in-hospital cardiac events and mortality after hip fracture surgery.

Conclusion · 2 of 2

Troponin levels greater than 100 ng/L identified patients at highest risk, independent of surgical delay. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Preoperative High-Sensitivity Troponin and Risk of In-Hospital Mortality and Cardiac Events after Hip Fracture Surgery.

Preoperative High-Sensitivity Troponin and Risk of In-Hospital Mortality and Cardiac Events after Hip Fracture Surgery.

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