Admission cognitive function independently predicts discharge walking function and functional independence…

Cohort studyJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association· Aug 2026

Admission cognitive function independently predicts discharge walking function and functional independence after stroke: a multicenter retrospective cohort study.

Jeong-Soo Kim, Eu Jeong Ko, In-Geon Hwang, Sang-Hyeok Lee

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Physical Medicine & RehabilitationCohort studyPrognosisQ1IF 2.1

Admission Mini-Mental State Examination cutoff of 20 predicts functional independence at stroke rehab discharge.

Admission cognitive function independently predicts discharge walking function and functional independence after stroke: a multicenter retrospective cohort study.

Jeong-Soo Kim … Sang-Hyeok Lee

Journal of stroke and cerebrovascular diseases · Aug 2026 · Q1 in Rehabilitation

Background

Post-stroke cognitive impairment is prevalent, yet its independent contribution to functional recovery during inpatient rehabilitation has not been adequately established in large multicenter cohorts.

Purpose

This study aimed to determine whether admission cognitive function, measured by the Mini-Mental State Examination (Mini-Mental State Examination), independently predicts discharge walking function and functional independence at discharge from inpatient stroke rehabilitation.

Methods

Were stratified by admission Mini-Mental State Examination into normal (≥24, n = 258), mild impairment (18-23, n = 98), and moderate-to-severe impairment (<18, n = 221) groups.

n = 258

AUC = 0.771

Results

AUC = 0.771

AUC 0.771 (0.5=chance, 1.0=perfect) for predicting independent function using Mini-Mental State Examination at admission.

n = 258

More results

Admission Mini-Mental State Examination independently predicted discharge Functional Ambulation Category (β = 0.013, p = 0.004) and discharge Modified Barthel Index (β = 0.736, p < 0.001).

The predictive effect was strongest in patients with severe motor impairment (Functional Ambulation Category 0-1; ρ = 0.585 for Modified Barthel Index, p < 0.001).

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Conclusion · 1 of 2

Admission Mini-Mental State Examination independently predicts discharge walking function and functional independence at rehabilitation discharge.

Conclusion · 2 of 2

An Mini-Mental State Examination score of 20 may serve as a clinically useful threshold for identifying patients at risk of poor functional outcomes. Routine cognitive screening at admission is recommended.

Admission cognitive function independently predicts discharge walking function and functional independence after stroke: a multicenter retrospective cohort study.

Admission cognitive function independently predicts discharge walking function and functional independence after stroke: a multicenter retrospective cohort study.

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