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Paper

Comparison of persons who died of drug overdoses with and without evidence of hepatitis C, United States, 2019-2024.

New research · Emergency Medicine

Drug and alcohol dependence · 3w

StudyDrug and alcohol dependence· Aug 2026

Comparison of persons who died of drug overdoses with and without evidence of hepatitis C, United States, 2019-2024.

Lauren J Tanz, Allison Ertl, Russell Mansfield, Shannon M Casillas

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Toxicology & PoisoningStudyQ1IF 3.6

Hepatitis C evidence among fatal overdoses rose from 5.3% to 7.2% by 2024.

Comparison of persons who died of drug overdoses with and without evidence of hepatitis C, United States, 2019-2024.

Lauren J Tanz … Shannon M Casillas

Drug and alcohol dependence · Aug 2026 · Q1 in Psychiatry

Background

Injection drug use is the most common risk factor for hepatitis C virus (hepatitis C virus) infection.

Purpose

This analysis compares sociodemographic characteristics and circumstances among overdose decedents with and without evidence of hepatitis C to inform prevention.

Methods

CDC's State Unintentional Drug Overdose Reporting System (State Unintentional Drug Overdose Reporting System) collects data on unintentional and undetermined intent drug overdose deaths, including hepatitis C virus infection information.

n = 328,754 decedents

Results

hepatitis C signal among overdose deaths is climbing, not fading

40.3%

With hepatitis C evide

23.9%

Without hepatitis C ev

“

Conclusion

Implementing community-based services to prevent infectious disease spread and overdose, accessible hepatitis C testing, linkage to substance use disorder treatment and curative hepatitis C treatment, and robust public health surveillance to identify populations for tailored prevention efforts might help address hepatitis C and drug use epidemics.

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