Sinusitis and Olfaction Improve in Young Children with Cystic Fibrosis Treated with ETI.

31 participants (mean age 4.8 years) enrolled, 27 initiated treatment, and 26 completed follow-up (mean treatment duration 1.0 years).

Following therapy, three olfactory measures improved: odor identification scores increased by 1.3 points (p = 0.03), olfactory bulb volume increased by 7.4mm3 (p = 0.02), and olfactory cleft opacification decreased by 14.4% (p = 0.004).

Quality of life scores remained at near-normal levels.