Impact of Medical Treatment on Nasal Discharge in Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis.

All four nasal discharge questions saw statistically significant improvement, with postnasal drip and thick nasal discharge seeing the largest degree of improvement (both -1.4 [95% CI: -2.3, -0.5).

Both patients with polyps (-39.2 [-49.2, -29.2]) and without nasal polyps (-26.0 [-41.9, -10.1]) saw significant improvement in rhinorrhea.

Only patients with polyps saw significant improvement in postnasal discharge (postnasal discharge) (-30.1 [-47.5, -12.7]).

Both biologic and standard medical treatments led to reductions in VAS Rhinorrhea, with biologics leading to a greater reduction ( P = .03).