Endoscopic resection of colitis-associated neoplasia: A scoping review.
Metachronous lesions develop in up to 31% of patients after endoscopic resection.
Endoscopic resection of colitis-associated neoplasia: A scoping review.
Ulcerative colitis (ulcerative colitis) increases the risk of colorectal dysplasia.
To summarize current evidence on the feasibility, safety, and outcomes of these techniques in ulcerative colitis-associated neoplasia.
A scoping review was conducted using PubMed and EMBASE (1975-May 2025) with the search: ("endoscopic submucosal dissection"/exp OR "endoscopic mucosal resection" OR "full thickness resection" OR "polypectomy") AND ("ulcerative colitis"/exp OR "ulcerative colitis" OR "pouch").
Endoscopic submucosal dissection achieved en bloc resection in 88%-100% and R0 resection in 73%-96% of cases.
The overall complication rate with endoscopic submucosal dissection was approximately 2%-10%, primarily bleeding or perforation.
Surgical intervention after endoscopic submucosal dissection was required in 10%-20% of patients, typically for non-curative resection or new lesions.
Endoscopic resection offers a spectrum of curative, minimally invasive options for managing dysplasia in ulcerative colitis.
endoscopic mucosal resection remains appropriate for simple, lifting lesions, while endoscopic submucosal dissection and endoscopic full-thickness resection broaden the therapeutic landscape for complex or fibrotic pathology.
Lesion morphology, lifting characteristics, and operator experience should guide technique selection.
Long-term outcomes are favorable with appropriate surveillance, though the risk of metachronous neoplasia necessitates continued monitoring.