An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning…

StudyThe Journal of bone and joint surgery. American volume· Jul 2026

An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning the Use of Orthobiologics.

Kyle N Kunze, Jacob T Morgan, Cameron Gerhold … Delphi Study Group

Shoulder & ElbowStudyClinical practiceQ1IF 3.2

Expert panel reached consensus on 96.8% of orthobiologics statements by final round.

An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning the Use of Orthobiologics.

Kyle N Kunze … Delphi Study Group

The Journal of bone and joint surgery · Jul 2026 · Q1 in Orthopedics

Background

The use of orthobiologics has received increasing interest given the potential positive treatment effects on symptoms and tissue regeneration.

Purpose

The purpose of this study was to create an international Delphi expert consensus statement on the use of orthobiologics in musculoskeletal medicine.

Methods

Were asked to respond to each statement using a Likert scale of "strongly disagree," "disagree," "neither disagree nor agree," "agree," and "strongly agree." The final consensus statement included those statements that achieved ≥70% agreement and <20% disagreement.

n = 24-member panel

Results

the panel agreed on almost every statement by the final round

48.1%

Round 1

96.8%

Round 3

More results

Sixty-two final statements were utilized in round 3.

Each round had 100% participation.

Some of the topics concerning platelet-rich plasma for rotator cuff repair augmentation and autologous cell-based therapies did not achieve consensus.

“

Conclusion · 1 of 2

A high degree of consensus was achieved across statements concerning appropriate use cases for various orthobiologic therapies.

Conclusion · 2 of 2

However, many of the adopted statements retained qualifying language, reflecting persistent areas of uncertainty in orthobiologic preparation, dosing, and indication-specific efficacy.

An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning the Use of Orthobiologics.

An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning the Use of Orthobiologics.

Related papers