Early Prediction of External Ventricular Drain Weaning Trial Outcome in Patients with SAH Based on ICP Pulse Morphological Similarity: A Single-Center Retrospective Cohort Analysis.

All models showed progressive performance improvement over time in predicting clamp trial result from the time of external ventricular drain clamping.

Clinical features provided modest improvements at early hours (5-18% AUC increase) with diminishing benefits later.

Decision curve analysis revealed incorporating clinical features enhanced clinical utility from 10 h onward, even with modest discriminative ability, while models achieved marked clinical utility at 16-24 h.