Indocyanine Green Fluorescent Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and…

Cohort studyThe Journal of surgical research· Aug 2026

Indocyanine Green Fluorescent Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and Meta-analysis.

Kawthar Faisal Kushara, Ahmed Salah Morad, Bushra Wadi Bin Saddiq … Suhail Abdullah Alturkistani

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Hepatobiliary & Pancreatic SurgeryCohort studyClinical practiceQ2IF 1.6

Indocyanine green fluorescent cholangiography shortens operative time versus conventional laparoscopic cholecystectomy.

Indocyanine Green Fluorescent Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and Meta-analysis.

Kawthar Faisal Kushara … Suhail Abdullah Alturkistani

The Journal of surgical research · Aug 2026 · Q2 in Surgery

Purpose

Laparoscopic cholecystectomy (laparoscopic cholecystectomy) is the standard treatment for gallbladder diseases.

Methods

Conducted according to PRISMA 2020 guidelines and registered in PROSPERO (CRD420251031001), we searched PubMed, Web of Science, Scopus, and Google Scholar from inception to November 2025.

n = 1198

Results

Indocyanine green shortens operative time versus conventional laparoscopic cholecystectomy

MD -8.53 (95% CI -12.85 to -4.21)

null 0

-12.85

-4.21

CI excludes the null - significant

More results

Subgroup analyses based on study design and country did not demonstrate significant differences in efficacy or safety.

“

Conclusion · 1 of 2

Indocyanine green fluorescent cholangiography appears to improve operative efficiency without compromising safety. However, variability among studies and methodological limitations preclude definitive conclusions.

Conclusion · 2 of 2

Large, high-quality randomized controlled trials are essential to fully elucidate the long-term effects of indocyanine green use.

Indocyanine Green Fluorescent Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and Meta-analysis.

Indocyanine Green Fluorescent Cholangiography in Laparoscopic Cholecystectomy: A Systematic Review and Meta-analysis.

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