A comprehensive model with dual plane ultrasound based deep learning radiomics to distinguish parotid…

AI / informaticsFrontiers in oncology· 2026

A comprehensive model with dual plane ultrasound based deep learning radiomics to distinguish parotid pleomorphic adenoma from Warthin tumor.

Yi Wang, An Dai, Zhaolin Yin … Ruoling Han

Medical Imaging AIAI / informaticsDiagnosisQ2IF 3.1

Combined nomogram model best distinguishes parotid pleomorphic adenoma from Warthin tumor

A comprehensive model with dual plane ultrasound based deep learning radiomics to distinguish parotid pleomorphic adenoma from Warthin tumor.

Yi Wang … Ruoling Han

Frontiers in oncology · 2026

Purpose

To develop and validate a dual-plane ultrasound (ultrasound)-based deep learning radiomics model for the noninvasive discrimination between parotid pleomorphic adenoma (pleomorphic adenoma) and Warthin tumor (warthin tumor).

Methods

This retrospective two-center study enrolled 656 patients with pathologically confirmed parotid tumors (361 pleomorphic adenoma, 295 warthin tumor).

n = 656 patients

Results

highest accuracy of all methods and physicians at telling the tumors apart

AUC 0.91 (95% CI 0.85 to 0.96)

null 0

0.85

0.96

CI excludes the null - significant

More results

The multi-channel fusion deep learning model (AUC = 0.860, 95%CI: 0.790-0.931) outperformed feature fusion (AUC = 0.818, 95%CI: 0.735-0.904).

It also exceeded the diagnostic performance of all physicians.

Model assistance improved junior physicians' AUC by 0.062 and specificity by 0.220; senior and expert physicians showed higher sensitivity and accuracy.

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Conclusion

The proposed dual-plane ultrasound-based deep learning radiomics model effectively differentiates pleomorphic adenoma from warthin tumor noninvasively, enhances diagnostic performance-particularly for less experienced physicians-and demonstrates potential for clinical translation.

A comprehensive model with dual plane ultrasound based deep learning radiomics to distinguish parotid pleomorphic adenoma from Warthin tumor.

A comprehensive model with dual plane ultrasound based deep learning radiomics to distinguish parotid pleomorphic adenoma from Warthin tumor.

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