Large Language Models as Health Information Tools: Patient Use and Trust in Otolaryngology.

AI / informaticsLaryngoscope investigative otolaryngology· Aug 2026

Large Language Models as Health Information Tools: Patient Use and Trust in Otolaryngology.

Beverly J Fu, Itzel Rubio-Jimenez, Alexander Ellman … Noel F Ayoub

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Large Language Models in CareAI / informaticsClinical practiceQ1IF 1.9

Most otolaryngology patients report having previously used large language models for health information.

Large Language Models as Health Information Tools: Patient Use and Trust in Otolaryngology.

Beverly J Fu … Noel F Ayoub

Laryngoscope investigative otolaryngology · Aug 2026

Purpose

Increasingly use large language models (large language models) for health information, yet their use patterns, perceptions, and impact on clinical communication in otolaryngology remain poorly characterized.

Methods

We conducted a cross-sectional survey of adult patients at an academic otolaryngology clinic.

n = 59 respondents

Results

Share of patients who had ever used an large language models for health information.

Prior LLM use

71.2%

Used before visit

28.6%

More results

All participants reported large language models information as helpful (50.0% very, 50.0% somewhat), that large language models information mostly (62.5%) or partially (25.0%) aligned with clinician explanations.

Most felt more prepared for the visit (46.7% much more, 40.0% somewhat more), yet trust remained moderate: 32.7% reported mostly or complete distrust.

More results

While concerns about accuracy (82.7%) and privacy (50.0%) were common, 46.2% were likely to use large language models again.

Most users (93.8%) did not disclose large language models use, although 56.2% believed clinicians should be aware.

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Conclusion · 1 of 2

Large language models use for health information is common among otolaryngology patients and associated with perceived benefit despite moderate trust and concerns.

Conclusion · 2 of 2

Engagement may be driven by factors beyond accuracy, including accessibility and perceived empathy. LEVEL OF EVIDENCE: 3.

Large Language Models as Health Information Tools: Patient Use and Trust in Otolaryngology.

Large Language Models as Health Information Tools: Patient Use and Trust in Otolaryngology.

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