Transversus Abdominis Plane Block With Dexmedetomidine and Local Anesthetics Compared With Local Anesthetics…

Meta-analysisThe Clinical journal of pain· Aug 2026

Transversus Abdominis Plane Block With Dexmedetomidine and Local Anesthetics Compared With Local Anesthetics Isolated for Patients Undergoing Cesarean Section: A Systematic Review and Meta-Analysis.

Laiz G Carneiro Novaes, Daniel M Oliveira, André B Donato … Thomas R Erdmann

Sedation & Anesthetic PharmacologyMeta-analysisTreatmentQ1IF 2.9

Dexmedetomidine added to transversus abdominis plane block lowers odds of needing rescue analgesia.

Transversus Abdominis Plane Block With Dexmedetomidine and Local Anesthetics Compared With Local Anesthetics Isolated for Patients Undergoing Cesarean Section: A Systematic Review and Meta-Analysis.

Laiz G Carneiro Novaes … Thomas R Erdmann

The Clinical journal of pain · Aug 2026 · Q1 in Anesthesiology

Purpose

Dexmedetomidine is a short-term sedative used for peripheral nerve blockade and spinal anesthesia.

Methods

Twelve randomized controlled trials (randomized controlled trials) encompassing 799 patients were included.

n = 799 patients

Results

dexmedetomidine cut the odds of needing rescue analgesia by about 75%

MD by subgroup · 95% CI

More results

DISCUSSION: Dexmedetomidine with local anesthetics was associated with a delay in consumption of the first analgesic in the postoperative period, a decrease in the amount of rescue intravenous tramadol, and a decrease in the visual analog scale scores at 6, 12, and 24 hours.

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Conclusion

DISCUSSION: Dexmedetomidine with local anesthetics was associated with a delay in consumption of the first analgesic in the postoperative period, a decrease in the amount of rescue intravenous tramadol, and a decrease in the visual analog scale scores at 6, 12, and 24 hours.

Transversus Abdominis Plane Block With Dexmedetomidine and Local Anesthetics Compared With Local Anesthetics Isolated for Patients Undergoing Cesarean Section: A Systematic Review and Meta-Analysis.

Transversus Abdominis Plane Block With Dexmedetomidine and Local Anesthetics Compared With Local Anesthetics Isolated for Patients Undergoing Cesarean Section: A Systematic Review and Meta-Analysis.

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