Sexual Function and Clinical Outcomes Following Rezūm Therapy for Benign Prostatic Hyperplasia: An Updated…

Systematic reviewLower urinary tract symptoms· Jul 2026

Sexual Function and Clinical Outcomes Following Rezūm Therapy for Benign Prostatic Hyperplasia: An Updated Systematic Review Including Large Prostate Volumes.

Ivan Maulana Fakh, Harrina Erlianti Rahardjo

Benign Prostatic DiseaseSystematic reviewTreatment

Severe complications after Rezūm therapy for benign prostatic hyperplasia occur in under 1%.

Sexual Function and Clinical Outcomes Following Rezūm Therapy for Benign Prostatic Hyperplasia: An Updated Systematic Review Including Large Prostate Volumes.

Ivan Maulana Fakh, Harrina Erlianti Rahardjo

Lower urinary tract symptoms · Jul 2026

Purpose

To evaluate sexual function and clinical outcomes following Rezūm water vapor thermal therapy (water vapor thermal therapy) for benign prostatic hyperplasia (benign prostatic hyperplasia), with a dedicated focus on patients with large prostate volumes (> 80 mL).

Methods

Methodological quality was appraised using the Newcastle-Ottawa Scale (Newcastle-Ottawa Scale) for 27 cohorts and the Cochrane RoB 2 tool for three randomized controlled trials (randomized controlled trials).

n = 4635 patients

< 1%

Results

< 1%

grade 3 or higher complications after treatment are rare

n = 4635 patients

More results

Thirty studies (N = 4635 patients) met inclusion criteria.

Across gland sizes (30-150 mL), Rezūm demonstrated a consistent trend toward preservation of erectile and ejaculatory function.

More results

Ten studies provided data for prostates > 80 mL; in this subgroup, Rezūm provided significant relief of lower urinary tract symptoms (lower urinary tract symptoms) with sexual function outcomes that appeared comparable to those in standard-sized glands.

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Conclusion · 1 of 2

Current evidence suggests that Rezūm preserves erectile and ejaculatory function while providing meaningful relief of urinary symptoms, including in large-volume prostates.

Conclusion · 2 of 2

However, confidence in these findings remains limited by the predominance of low-quality evidence and a high risk of bias.

Sexual Function and Clinical Outcomes Following Rezūm Therapy for Benign Prostatic Hyperplasia: An Updated Systematic Review Including Large Prostate Volumes.

Sexual Function and Clinical Outcomes Following Rezūm Therapy for Benign Prostatic Hyperplasia: An Updated Systematic Review Including Large Prostate Volumes.

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