Prediction effect of chronic inflammatory marker MLR and clinical Metric on postoperative symptom recovery in patients with BPH and Non-Linearity Association Analysis.
Higher preoperative monocyte-to-lymphocyte ratio linked to poor symptom recovery after prostate surgery
Prediction effect of chronic inflammatory marker MLR and clinical Metric on postoperative symptom recovery in patients with BPH and Non-Linearity Association Analysis.
To explore the predictive value of preoperative systemic inflammatory markers combined with clinical parameters for the improvement of lower urinary tract symptoms in patients with lower urinary tract symptoms (lower urinary tract symptoms) secondary to benign prostatic obstruction (benign prostatic obstruction) after surgery.
This study was a single-center observational cohort study that consecutively enrolled 180 patients with benign prostatic hyperplasia (benign prostatic hyperplasia) who underwent transurethral prostate surgery.
higher monocyte-to-lymphocyte ratio meant worse odds of symptom recovery
Preoperative postvoid residual urine volume, MLR, and total prostate-specific antigen levels in the poor symptom response group were significantly higher than those in the good response group (P < 0.05).
Generalized additive model analysis further revealed a nonlinear association: when postvoid residual urine volume was greater than 90 mL, its negative impact on the improvement of postoperative storage symptoms was significantly intensified; the negative effects tended to ease after MLR > 0.25.
Preoperative MLR, postvoid residual urine volume, and prostate-specific antigen level are independent factors for predicting the improvement of postoperative symptoms in patients patients with benign prostatic obstruction..
Among them, MLR, as a biomarker reflecting the state of chronic inflammation, has specific predictive value for the improvement of storage symptoms.
These preoperative parameters are helpful in identifying high-risk patients with poor postoperative symptom improvement and provide references for individualized clinical decision-making.