SheVari4 ® , a proprietary root extract from Asparagus racemosus , ameliorates menopausal health: insights…

Randomized trialFood & nutrition research· 2026

SheVari4 ® , a proprietary root extract from Asparagus racemosus , ameliorates menopausal health: insights from a randomized, double-blind, placebo controlled clinical trial.

Raktim Chattopadhyay, Subhankar Karmakar, Tandra R Chakraborty … Debasis Bagchi

Menopause & Hormone TherapyRandomized trialTreatmentQ1IF 4.4

Shatavari extract cut menopause symptom-burden score 42.8% more than placebo.

SheVari4 ® , a proprietary root extract from Asparagus racemosus , ameliorates menopausal health: insights from a randomized, double-blind, placebo controlled clinical trial.

Raktim Chattopadhyay … Debasis Bagchi

Food & nutrition research · 2026

Purpose

Menopause marks the natural end of reproductive phase of women caused by decline in levels of estrogen, progesterone and other reproductive hormones.

Methods

Sixty women (age 50.0 ± 7.4 years) randomized in two equal groups were administered with 100 mg SheVari4 ® or placebo capsules once daily for 8 weeks.

n = 60 pre-, peri-, and post-menopausal

Results

42.8%

greater relief from hot flashes, mood, and other symptoms than placebo

n = 60 pre-, peri-, and post-menopausal

More results

The formulation also increased E2 (+36.44% vs. -2.08%) and progesterone (+0.30% vs. -2.88%) coupled with marked reduction in levels of Follicle Stimulating Hormone (-38.18% vs. +12.97%) and cortisol (-26.87% vs. +17.16%).

Concomitantly, Anti Mullerian Hormone, Sex Hormone-Binding Globulin, and free testosterone were also favorably modulated.

More results

Blood biochemistry, liver function tests, and vital signs confirmed the broad-spectrum safety of SheVari4 ® .

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Conclusion

SheVari4 ® significantly improved menopause-specific QOL and endocrine parameters in peri- and post-menopausal women, with a well-established safety profile.

SheVari4 ® , a proprietary root extract from Asparagus racemosus , ameliorates menopausal health: insights from a randomized, double-blind, placebo controlled clinical trial.

SheVari4 ® , a proprietary root extract from Asparagus racemosus , ameliorates menopausal health: insights from a randomized, double-blind, placebo controlled clinical trial.

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